PTPRD antibody (N-Term)

Catalog No. ABIN653540

Product Details anti-PTPRD Antibody

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Binding Specificity: AA 343-371, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPRD antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PTPRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-371 amino acids from the N-terminal region of human PTPRD.

Clone: RB25179

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PTPRD

Target: PTPRD (Protein tyrosine Phosphatase, Receptor Type, D (PTPRD))

Alternative Name: PTPRD (PTPRD Products)

Synonyms: HPTP antibody, HPTPD antibody, HPTPDELTA antibody, PTPD antibody, RPTPDELTA antibody, 1110002J03Rik antibody, 3000002J10Rik antibody, B230219D21Rik antibody, R-PTP-delta antibody, ptprd antibody, zgc:165626 antibody, ptpdelta antibody, rptpdelta antibody, xptp-d antibody, protein tyrosine phosphatase, receptor type D antibody, protein tyrosine phosphatase, receptor type, D antibody, receptor-type tyrosine-protein phosphatase delta antibody, protein tyrosine phosphatase, receptor type, D, b antibody, protein tyrosine phosphatase, receptor type D S homeolog antibody, PTPRD antibody, Ptprd antibody, LOC100155429 antibody, ptprdb antibody, ptprd.S antibody

Background: PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.

Molecular Weight: 214760

Gene ID: 5789

NCBI Accession: NP_001164496, NP_002830, NP_569075, NP_569076

UniProt: P23468

Pathways: Synaptic Membrane