RPSA/Laminin Receptor antibody (AA 190-240)

Catalog No. ABIN5690234

This anti-RPSA/Laminin Receptor antibody is a Rabbit Polyclonal antibody detecting RPSA/Laminin Receptor in WB, ELISA, IF and IHC (p). Suitable for Human and Mouse.

Quick Overview for RPSA/Laminin Receptor antibody (AA 190-240) (ABIN5690234)

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPSA/Laminin Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RPSA/Laminin Receptor Antibody

Binding Specificity: AA 190-240

Specificity: RPSA antibody is human, mouse and rat reactive.

Purification: RPSA antibody is affinity chromatography purified via peptide column.

Immunogen: RPSA antibody was raised against a 17 amino acid peptide near the carboxy terminus of human RPSA.

The immunogen is located within amino acids 190 - 240 of RPSA.

Isotype: IgG

Application Details

Application Notes: RPSA antibody can be used for detection of RPSA by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: RPSA antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RPSA antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Target Details for RPSA/Laminin Receptor

Target: RPSA/Laminin Receptor (RPSA) (Ribosomal Protein SA (RPSA))

Alternative Name: RPSA

Background: The 40S ribosomal protein SA (RPSA) is a high-affinity, non-integrin family, laminin receptor, also known as 67 kDa laminin receptor or 37 kDa laminin receptor precursor (37LRP) (1). Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes and have been implicated in a variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis (2). RPSA is overexpressed in multiple types of cancers and has recently been shown to act as a cancer-specific death receptor (3).

Molecular Weight: Predicted: 32 kDa

Observed: 32 kDa

Gene ID: 3921

NCBI Accession: NP_002286

UniProt: P08865

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly