MXD1 antibody (AA 1-221)

Catalog No. ABIN5692892

This anti-MXD1 antibody is a Rabbit Polyclonal antibody detecting MXD1 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for MXD1 antibody (AA 1-221) (ABIN5692892)

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MXD1 Antibody

Binding Specificity: AA 1-221

Purpose: Anti-Mad/MXD1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Mad/MXD1 Antibody (ABIN5692892). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Mad recombinant protein (Position: M1-L221).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for MXD1

Target: MXD1 (MAX Dimerization Protein 1 (MXD1))

Alternative Name: MXD1

Background:

Synonyms: Max dimerization protein 1, Max dimerizer 1, Protein MAD, MXD1, MAD

Background: MAD protein is a protein that in humans is encoded by the MXD1 gene. This gene encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molecular Weight: 28 kDa

Gene ID: 4084

UniProt: Q05195