PSD antibody (AA 536-803)

Catalog No. ABIN5692916

Product Details anti-PSD Antibody

Target: PSD (Pleckstrin and Sec7 Domain Protein (PSD))

Binding Specificity: AA 536-803

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSD antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Anti-PSD Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-PSD Antibody Picoband® (ABIN5692916). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived human PSD recombinant protein (Position: T536-K803).

Isotype: IgG

Application Details

Application Notes: Western blot,0.1-0.5 μg/mL
ELISA,0.1-0.5 μg/mL
1. Derrien, V., Couillault, C., Franco, M., Martineau, S., Montcourrier, P., Houlgatte, R., Chavrier, P. A conserved C-terminal domain of EFA6-family ARF6-guanine nucleotide exchange factors induces lengthening of microvilli-like membrane protrusions. J. Cell Sci. 115: 2867-2879, 2002. 2. Perletti, L., Talarico, D., Trecca, D., Ronchetti, D., Fracchiolla, N. S., Maiolo, A. T., Neri, A. Identification of a novel gene, PSD, adjacent to NFKB2/lyt-10, which contains Sec7 and pleckstrin-homology domains. Genomics 46: 251-259, 1997.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for PSD

Target: PSD (Pleckstrin and Sec7 Domain Protein (PSD))

Alternative Name: PSD (PSD Products)

Background:

Synonyms: PH and SEC7 domain-containing protein 1, Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6, Exchange factor for ARF6, Exchange factor for ARF6 A, Pleckstrin homology and SEC7 domain-containing protein 1, PSD, EFA6, EFA6A

Tissue Specificity: Isoform 2 is expressed in the brain.

Background: PSD, which called EFA6A, is 63 % identical to EFA6B (PSD4) and contains a Sec7 domain adjacent to a PH domain, followed by a C-terminal coiled-coil motif. This gene is mapped to chromosome 10q24. And it encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.

Molecular Weight: 130 kDa

Gene ID: 5662