PLIN1 antibody (DyLight 488)

Catalog No. ABIN7354757

The Rabbit Polyclonal anti-PLIN1 antibody has been validated for FACS. It is suitable to detect PLIN1 in samples from Human.

Quick Overview for PLIN1 antibody (DyLight 488) (ABIN7354757)

Target: PLIN1 (Perilipin 1 (PLIN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLIN1 antibody is conjugated to DyLight 488

Application: Flow Cytometry (FACS)

Product Details anti-PLIN1 Antibody (DyLight 488)

Purpose: Anti-Human Perilipin A DyLight® 488 conjugated PLIN1 Antibody

Sequence: DKVLGAALAG CELAWGVARD TAEFAANTRA GRLAS

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Human Perilipin A DyLight® 488 conjugated PLIN1 Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Perilipin A, which shares 80% amino acid (aa) sequence identity with both mouse and rat Perilipin A.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. Brasaemle DL, Subramanian V, Garcia A, Marcinkiewicz A, Rothenberg A (June 2009). "Perilipin A and the control of triacylglycerol metabolism". Mol. Cell. Biochem. 326 (1-2): 15-21. 2. Greenberg AS, Egan JJ, Wek SA, Garty NB, Blanchette-Mackie EJ, Londos C (June 1991). "Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets". J. Biol. Chem. 266 (17): 11341-6.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Target Details for PLIN1

Target: PLIN1 (Perilipin 1 (PLIN1))

Alternative Name: PLIN1

Background:

Synonyms: Perilipin-1, Lipid droplet-associated protein, PLIN1, PERI, PLIN

Tissue Specificity: Adipocytes.

Background: Perilipin, also known as lipid droplet-associated protein or PLIN, is a protein that, in humans, is encoded by the PLIN gene. The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis.

Molecular Weight: 39 kDa

Gene ID: 5346

UniProt: O60240

Pathways: Lipid Metabolism