AMOTL2 antibody (AA 401-480)

Catalog No. ABIN5692981

Product Details anti-AMOTL2 Antibody

Target: AMOTL2 (Angiomotin Like 2 (AMOTL2))

Binding Specificity: AA 401-480

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMOTL2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purpose: Anti-AMOTL2 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-AMOTL2 Antibody Picoband® (ABIN5692981). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived human AMOTL2 recombinant protein (Position: A401-Q480).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Li, Z., Wang, Y., Zhang, M., Xu, P., Huang, H., Wu, D., Meng, A. The Amotl2 gene inhibits Wnt/B-catenin signaling and regulates embryonic development in zebrafish. J. Biol. Chem. 287: 13005-13015, 2012. 2. Wang, Y., Li, Z., Xu, P., Huang, L., Tong, J., Huang, H., Meng, A. Angiomotin-like2 gene (amotl2) is required for migration and proliferation of endothelial cells during angiogenesis. J. Biol. Chem. 286: 41095-41104, 2011.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for AMOTL2

Target: AMOTL2 (Angiomotin Like 2 (AMOTL2))

Alternative Name: AMOTL2 (AMOTL2 Products)

Background:

Synonyms: Angiomotin-like protein 2, Leman coiled-coil protein, LCCP, AMOTL2, KIAA0989

Background: Angiomotin-like protein 2 is a protein that in humans is encoded by the AMOTL2 gene. Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). It mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motin protein family. Alternative splicing results in multiple transcript variants of this gene.

Molecular Weight: 95 kDa

Gene ID: 51421

UniProt: Q9Y2J4