PROS1 antibody (AA 291-676)

Catalog No. ABIN5693293

The Rabbit Polyclonal anti-PROS1 antibody has been validated for WB and ELISA. It is suitable to detect PROS1 in samples from Human.

Quick Overview for PROS1 antibody (AA 291-676) (ABIN5693293)

Target: PROS1 (PROS) (Protein S (PROS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PROS1 Antibody

Binding Specificity: AA 291-676

Purpose: Anti-Protein S/PROS1 Antibody Picoband®

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Protein S/PROS1 Antibody Picoband® (ABIN5693293). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived human Protein S recombinant protein (Position: L291-S676).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Long GL, Marshall A, Gardner JC, Naylor SL (January 1988). "Genes for human vitamin K-dependent plasma proteins C and S are located on chromosomes 2 and 3, respectively". Somat. Cell Mol. Genet. 14 (1): 93-8. 2. Dahlbäck B, Lundwall A, Stenflo J (Jun 1986). "Primary structure of bovine vitamin K-dependent protein S". Proceedings of the National Academy of Sciences. 83 (12): 4199-203.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Target Details for PROS1

Target: PROS1 (PROS) (Protein S (PROS))

Alternative Name: PROS1

Background:

Synonyms: Vitamin K-dependent protein S, PROS1, PROS

Tissue Specificity: Plasma.

Background: This PROS1 gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Molecular Weight: 75 kDa

Gene ID: 5627

UniProt: P07225