Complexin 1 antibody

Catalog No. ABIN5697449

The Rabbit Polyclonal anti-Complexin 1 antibody has been validated for WB, ELISA, IHC, IF and IP. It is suitable to detect Complexin 1 in samples from Human, Mouse and Rat.

Quick Overview for Complexin 1 antibody (ABIN5697449)

Target: Complexin 1 (CPLX1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Complexin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-Complexin 1 Antibody

Immunogen: complexin 1

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab01920(CPLX1 antibody) at dilution of 1:1500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Expiry Date: 12 months

Target Details for Complexin 1

Target: Complexin 1 (CPLX1)

Alternative Name: CPLX1

Background: Synonyms:complexin 1, Complexin I, complexin1, CPLX1, CPX I, CPX1, Synaphin 2 Background:Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles(PubMed:21785414). Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse(PubMed:21785414). Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior.

Molecular Weight: 15-20 kDa

Gene ID: 10815

UniProt: O14810

Pathways: Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport