AGO2 antibody (AA 620-859)

Catalog No. ABIN5697645

This anti-AGO2 antibody is a Rabbit Polyclonal antibody detecting AGO2 in WB, ELISA and IP. Suitable for Human, Mouse and Rat.

Quick Overview for AGO2 antibody (AA 620-859) (ABIN5697645)

Target: AGO2 (Argonaute 2 (AGO2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-AGO2 Antibody

Binding Specificity: AA 620-859

Purpose: AGO2 antibody

Immunogen:

Immunogen sequence: 620-859aa

Immunogen: eukaryotic translation initiation factor 2C, 2

Isotype: IgG

Application Details

Application Notes: WB :1:200-1:2000,IP:1:200-1:2000

Comment:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab00214(EIF2C2 antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for AGO2

Target: AGO2 (Argonaute 2 (AGO2))

Alternative Name: AGO2

Background:

Synonyms: Protein argonaute-2 (Argonaute2, hAgo2)|Argonaute RISC catalytic component 2|Eukaryotic translation initiation factor 2C 2 (eIF-2C 2, eIF2C 2)|PAZ Piwi domain protein (PPD)|Protein slicer|AGO2|EIF2C2

Background: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 97kDa

Gene ID: 27161

UniProt: Q9UKV8

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization