UMPS antibody

Catalog No. ABIN5698683

The Rabbit Polyclonal anti-UMPS antibody (ABIN5698683) specifically detects UMPS in WB, IHC, ELISA and IP. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for UMPS antibody (ABIN5698683)

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UMPS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-UMPS Antibody

Purpose: UMPS antibody

Immunogen: uridine monophosphate synthetase

Isotype: IgG

Application Details

Application Notes: WB : 1:500-1:5000,IP:1:200-1:2000,IHC:1:20-1:200

Comment:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab09253(UMPS antibody) at dilution of 1:400

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for UMPS

Target: UMPS (Uridine Monophosphate Synthetase (UMPS))

Alternative Name: UMPS

Background:

Synonyms: Uridine 5'-monophosphate synthase (UMP synthase)|UMPS

Background: This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.

Molecular Weight: 26kDa

Gene ID: 7372

UniProt: P11172

Pathways: Ribonucleoside Biosynthetic Process