STING1 (AA 170-379) antibody

Catalog No. ABIN5701799

The Rabbit Polyclonal anti- antibody has been validated for WB, IHC, ELISA, FACS, IF and IP. It is suitable to detect in samples from Human, Mouse and Rat.

Quick Overview for STING1 (AA 170-379) antibody (ABIN5701799)

Target: STING1

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details

Binding Specificity: AA 170-379

Purpose: STING1 antibody

Immunogen:

Immunogen sequence: 170-379aa

Immunogen: transmembrane protein 173

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab08759(TMEM173 antibody) at dilution of 1:500

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details

Target: STING1

Background:

Synonyms: Stimulator of interferon genes protein (hSTING)|Endoplasmic reticulum interferon stimulator (ERIS)|Mediator of IRF3 activation (hMITA)|Transmembrane protein 173|STING1|ERIS|MITA|STING|TMEM173

Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Gene ID: 340061

UniProt: Q86WV6