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ERK1/2 antibody

This Rabbit Polyclonal antibody specifically detects ERK1/2 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse, Rat and Zebrafish (Danio rerio).
Catalog No. ABIN5702776

Quick Overview for ERK1/2 antibody (ABIN5702776)

Target

See all ERK1/2 (MAPK1/3) Antibodies
ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

Reactivity

  • 179
  • 156
  • 150
  • 21
  • 21
  • 18
  • 6
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat, Zebrafish (Danio rerio)

Host

  • 139
  • 43
  • 4
Rabbit

Clonality

  • 133
  • 53
Polyclonal

Conjugate

  • 84
  • 9
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
This ERK1/2 antibody is un-conjugated

Application

  • 139
  • 66
  • 51
  • 51
  • 44
  • 35
  • 24
  • 24
  • 20
  • 13
  • 5
  • 4
  • 3
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Immunogen

    mitogen-activated protein kinase 1

    Isotype

    IgG
  • Application Notes

    WB : 1:1000-1:10000 IHC : 1:50-1:200 IF : 1:10-1:100

    Comment

    HeLa cells were subjected to SDS PAGE followed by western blot with FNab02845(ERK1/2 antibody) at dilution of 1:1000

    Restrictions

    For Research Use only
  • Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze / thaw cycles.

    Storage

    -20 °C

    Expiry Date

    12 months
  • Target

    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))

    Alternative Name

    ERK1/2

    Background

    Synonyms:ERK, ERK 2, ERK1/2, ERK2, ERT1, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAPK 1, MAPK 2, MAPK1, MAPK2, p40, p41, p41mapk, p42 MAPK, P42MAPK, PRKM1, PRKM2 Background:This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

    Molecular Weight

    38-44 kDa

    UniProt

    P28482
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