PEX19 antibody
Quick Overview for PEX19 antibody (ABIN5704133)
Target
See all PEX19 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Immunogen
- peroxisomal biogenesis factor 19
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Isotype
- IgG
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Application Notes
- WB : 1:200-1:2000 IP : 1:200-1:1000 IHC : 1:20-1:200
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Comment
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human heart tissue were subjected to SDS PAGE followed by western blot with FNab06329(PEX19 antibody) at dilution of 1:300
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze / thaw cycles.
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Storage
- -20 °C
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Expiry Date
- 12 months
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- PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))
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Alternative Name
- PEX19
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Background
- Synonyms:33 kDa housekeeping protein, D1S2223E, HK33, Peroxin 19, PEX19, PMP1, PMPI, PXF, PXMP1 Background:This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 35-40 kDa
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Gene ID
- 5824
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UniProt
- P40855
Target
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