SIKE1 antibody
Quick Overview for SIKE1 antibody (ABIN5705251)
Target
See all SIKE1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Immunogen
- suppressor of IKK epsilon
-
Isotype
- IgG
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07867(SIKE1 antibody) at dilution of 1:500
-
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handling Advice
- Avoid repeated freeze / thaw cycles.
-
Storage
- -20 °C
-
Expiry Date
- 12 months
-
-
- SIKE1 (Suppressor of IKBKE 1 (SIKE1))
-
Alternative Name
- SIKE1
-
Background
- Synonyms:SIKE Background:Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements(ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
-
Gene ID
- 80143
-
UniProt
- Q9BRV8
Target
-