The Rabbit Polyclonal anti-LRRC8C antibody has been validated for ELISA, IF and IHC. It is suitable to detect LRRC8C in samples from Human, Mouse and Rat.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze / thaw cycles.
Storage
-20 °C
Expiry Date
12 months
Target
LRRC8C
(Leucine Rich Repeat Containing 8 Family, Member C (LRRC8C))
Alternative Name
LRRC8C
Background
Synonyms:AD158, FAD158 Background:Non-essential component of the volume-regulated anion channel(VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member(LRRC8B, LRRC8C, LRRC8D or LRRC8E), channel characteristics depend on the precise subunit composition.