Clusterin antibody (AA 184-293)

Catalog No. ABIN5706111

This anti-Clusterin antibody is a Rabbit Polyclonal antibody detecting Clusterin in WB, IHC, ELISA and IP. Suitable for Human, Rat and Mouse.

Quick Overview for Clusterin antibody (AA 184-293) (ABIN5706111)

Target: Clusterin (CLU)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Clusterin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-Clusterin Antibody

Binding Specificity: AA 184-293

Purpose: CLU antibody

Immunogen:

Immunogen sequence: 184-293aa

Immunogen: clusterin

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:5000,IP:1:200-1:2000,IHC:1:50-1:200

Comment:

Y79 cells were subjected to SDS PAGE followed by western blot with FNab01781(CLU antibody) at dilution of 1:300

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Clusterin

Target: Clusterin (CLU)

Alternative Name: CLU

Background:

Synonyms: Clusterin|Aging-associated gene 4 protein|Apolipoprotein J (Apo-J)|Complement cytolysis inhibitor (CLI)|Complement-associated protein SP-40,40|Ku70-binding protein 1|NA1/NA2|Sulfated glycoprotein 2 (SGP-2)|Testosterone-repressed prostate message 2 (TRPM-2)|Clusterin beta chain Alternative names: ApoJalpha|Complement cytolysis inhibitor a chain|SP-40,40 beta-chain|Clusterin alpha chain Alternative names: ApoJbeta|Complement cytolysis inhibitor b chain|SP-40,40 alpha-chain|CLU|APOJ|CLI|KUB1

Background: The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.

Molecular Weight: 70-80 kDa and 50 kDa

UniProt: P10909

Pathways: Apoptosis, Negative Regulation of intrinsic apoptotic Signaling