TREX2 antibody (Internal Region)

Catalog No. ABIN570670

This Goat Polyclonal antibody specifically detects TREX2 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for TREX2 antibody (Internal Region) (ABIN570670)

Target: TREX2 (Trex2) (three Prime Repair Exonuclease 2 (Trex2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TREX2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Grade: Verified

Product Details anti-TREX2 Antibody

Binding Specificity: Internal Region

Purpose: TREX2

Sequence: HRSSLENPEH DES

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-HRSSLENPEHDES, from the internal region of the protein sequence according to NP_542432.2.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: In paraffin embedded Human Breast shows nuclear staining in the luminal epithelial duct cells. Recommended concentration, 3-6 μg/mL.

Western Blot: Preliminary experiments gave an approx 18 kDa band in lysates of Jurkat, MOLT4 and U937 after 0.5 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculate

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for TREX2

Target: TREX2 (Trex2) (three Prime Repair Exonuclease 2 (Trex2))

Alternative Name: TREX2

Background: Three prime repair exonuclease 2, 3'-5' exonuclease

Gene ID: 11219

NCBI Accession: NP_542432