IL18BP antibody (AA 29-193)

Catalog No. ABIN5708089

This anti-IL18BP antibody is a Rabbit Polyclonal antibody detecting IL18BP in WB and ELISA. Suitable for Mouse and Rat.

Quick Overview for IL18BP antibody (AA 29-193) (ABIN5708089)

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL18BP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL18BP Antibody

Binding Specificity: AA 29-193

Purification: Antigen affinity purified

Immunogen: A recombinant mouse partial protein corresponding to amino acids T29-A193 was used as the immunogen for the Il18bp antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Il18bp antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,ELISA (Capture): 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Il18bp antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for IL18BP

Target: IL18BP (Interleukin 18 Binding Protein (IL18BP))

Alternative Name: Il18 binding protein

Background: Interleukin-18-binding protein is a protein that in humans is encoded by the IL18BP gene. The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UniProt: Q9Z0M9