S100A7 antibody

Catalog No. ABIN5708274

The Rabbit Polyclonal anti-S100A7 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect S100A7 in samples from Human, Mouse and Rat.

Quick Overview for S100A7 antibody (ABIN5708274)

Target: S100A7 (S100 Calcium Binding Protein A7 (S100A7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-S100A7 Antibody

Purification: Antigen affinity purified

Immunogen: A recombinant human partial protein corresponding to amino acids S2-Q101 was used as the immunogen for the Psoriasin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Psoriasin antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Psoriasin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for S100A7

Target: S100A7 (S100 Calcium Binding Protein A7 (S100A7))

Alternative Name: S100A7 / Psoriasin

Background: S100 calcium-binding protein A7 (S100A7), also known as psoriasin, is a protein that in humans is encoded by the S100A7 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.

UniProt: P31151

Pathways: S100 Proteins