GAP43 antibody

Catalog No. ABIN576271

This Rabbit Polyclonal antibody specifically detects GAP43 in WB, IHC, IP and IHC (fro). It exhibits reactivity toward Human, Rat, Mouse and Monkey.

Quick Overview for GAP43 antibody (ABIN576271)

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Reactivity: Human, Rat, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAP43 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GAP43 Antibody

Specificity: Recognizes the protein designated GAP43, a neuronal protein that is expressed at elevated levels during development and also during regenerative axon growth. GAP43 (also known as neuromodulin, pp46, B-50, Protein F1 and calmodulin-binding protein P-57) is a protein of approximately 25kD that migrates on SDS-PAGE gels with an apparent size of 40-50kD. The aberrant migration is due to the unusually low abundance of hydrophobic amino acid residues. GAP43 is found tightly associated with neuronal membranes due to palmitoylation. The solubilized protein binds calmodulin, although this is reduced following protein kinase C phosphorylation of GAP43.

Immunogen: Purified rat GAP-43.

Type of Immunogen: Purified protein

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-Fr, IP, WB (1:500 - 1:1000)

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Serum, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for GAP43

Target: GAP43 (Growth Associated Protein 43 (GAP43))

Alternative Name: GAP43

Background: Name/Gene ID: GAP43
Family: Neuromodulin

Synonyms: GAP43, Axonal membrane protein GAP-43, B-50, Growth associated protein 43, Growth-associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46, GAP-43, Protein F1

Gene ID: 2596