PGD antibody (AA 1-483)

Catalog No. ABIN5775894

This Mouse Monoclonal antibody specifically detects PGD in WB, ELISA, IF and ICC. It exhibits reactivity toward Human.

Quick Overview for PGD antibody (AA 1-483) (ABIN5775894)

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PGD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT46B3

Product Details anti-PGD Antibody

Binding Specificity: AA 1-483

Immunogen: Recombinant human PGD (1-483aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for PGD

Target: PGD (Phosphogluconate Dehydrogenase (PGD))

Alternative Name: 6-phosphogluconate Dehydrogenase/PGD

Background: PGD (Phosphogluconate dehydrogenas), also known as 6PGD, is a 483 amino acid enzyme that is involved in the pentose phosphate shunt. Pentose is required for nucleic acid biosynthesis and the pentose phosphate cycle is a major source of NADPH. PGD deficiency increases the level of erythrocyte pyruvate kinase (PK) activity and reduces glutathione synthetase (GSH), resulting in hemolysis. Defects in PGD are generally asymptomatic and are inherited in an autosomal dominant fashion.

NCBI Accession: NP_002622