Aminoacylase 1 antibody (AA 1-408)

Catalog No. ABIN5775904

The Mouse Monoclonal anti-Aminoacylase 1 antibody has been validated for WB, ELISA, FACS, IF and ICC. It is suitable to detect Aminoacylase 1 in samples from Human.

Quick Overview for Aminoacylase 1 antibody (AA 1-408) (ABIN5775904)

Target: Aminoacylase 1 (ACY1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aminoacylase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT1E2

Product Details anti-Aminoacylase 1 Antibody

Binding Specificity: AA 1-408

Purpose: Human Aminoacylase/ACY1 antibody

Purification: Purified

Immunogen: Recombinant human ACY1 (1-408aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for Aminoacylase 1

Target: Aminoacylase 1 (ACY1)

Alternative Name: Aminoacylase/ACY1

Background: Aminoacylase-1, also designated N-acyl-L-amino-acid amidohydrolase or ACY1, is a member of the largest metallopeptidase family called M20A. Aminoacylase-1 is a zinc-binding homodimeric enzyme expressed in kidney, brain, placenta and spleen. It is the most abundant of the aminoacylases. Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D). ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. All affected individuals exhibit markedly increased urinary excretion of several N-acetylated amino acids.

NCBI Accession: NP_000657