SBDS antibody (AA 1-250)

Catalog No. ABIN5775988

The Mouse Monoclonal anti-SBDS antibody has been validated for WB, ELISA, IF and ICC. It is suitable to detect SBDS in samples from Human.

Quick Overview for SBDS antibody (AA 1-250) (ABIN5775988)

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SBDS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT1E8

Product Details anti-SBDS Antibody

Binding Specificity: AA 1-250

Immunogen: Recombinant human SBDS (1-250aa) purified from E. coli

Isotype: IgG2b kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for SBDS

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Alternative Name: SBDS

Background: The Shwachman-Bodian-Diamond syndrome (SBDS) is 249 amino acid ribosome maturation protein. The precise function of the SBDS protein is not known but it appears to play an important role in actin cytoskeletal function and mitotic spindle stabilization. Also, SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Mutations in the SBDS gene cause Shwachman-Diamond syndrome (SDS). SDS is an autosomal recessive disorder with clinical features that include pancreatic exocrine insufficiency, haematological dysfunction and skeletal abnormalities.

NCBI Accession: NP_057122

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly