DKK3 antibody (AA 22-350)

Catalog No. ABIN5776012

The Mouse Monoclonal anti-DKK3 antibody has been validated for WB and ELISA. It is suitable to detect DKK3 in samples from Human.

Quick Overview for DKK3 antibody (AA 22-350) (ABIN5776012)

Target: DKK3

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DKK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: AT103B5

Product Details anti-DKK3 Antibody

Binding Specificity: AA 22-350

Purpose: Human DKK3 antibody

Purification: Purified

Immunogen: Recombinant human DKK3 (22-350aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for DKK3

Target: DKK3

Background: Dickkopf-related protein 3, also known as DKK3, is a member of the DKK protein family including Dkk-1, 2, 3 and -4. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. DKK3 is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.

NCBI Accession: NP_001018067