KRT17 antibody (AA 1-432)
Quick Overview for KRT17 antibody (AA 1-432) (ABIN5776077)
Target
See all KRT17 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-432
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Immunogen
- Recombinant human KRT17(1-432aa) purified from E. coli
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Isotype
- IgG2a kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- KRT17 (Keratin 17 (KRT17))
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Alternative Name
- Cytokeratin 17/KRT17
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Background
- Keratins (cytokeratins) are intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments. Keratin 17 is involved in wound healing and cell growth, two processes that require rapid cytoskeletal remodeling. Keratinocytes deficient in keratin 17 exhibit abnormal Akt/mTOR signaling and fail to produce an increase in translation, cell size, or growth, these cells also exhibit abnormal 14-3-3 sigma localization.
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NCBI Accession
- NP_000413
Target
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