GOT2 antibody (AA 30-430)

Catalog No. ABIN5776157

This anti-GOT2 antibody is a Mouse Monoclonal antibody detecting GOT2 in WB, ELISA, ICC, IF and FACS. Suitable for Human.

Quick Overview for GOT2 antibody (AA 30-430) (ABIN5776157)

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GOT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: AT8B11

Product Details anti-GOT2 Antibody

Binding Specificity: AA 30-430

Immunogen: Recombinant human GOT2 (30-430aa) purified from E.coli

Isotype: IgG3 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for GOT2

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Alternative Name: GOT2

Background: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. Also, GOT2 is a major participant in the malate-aspartate shuttle, which is a passage from the cytosol to the mitochondria. The two enzymes are homodimeric and show close homology. GOT2 has been seen to have a role in cell proliferation, especially in terms of tumor growth.

NCBI Accession: NP_002071

Pathways: Monocarboxylic Acid Catabolic Process