VTA1 antibody (AA 1-307)
Quick Overview for VTA1 antibody (AA 1-307) (ABIN5776242)
Target
See all VTA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 1-307
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Immunogen
- Recombinant human VTA1 (1-307aa) purified from E. coli
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Isotype
- IgG1 kappa
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- VTA1 (Vps20-Associated 1 Homolog (VTA1))
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Alternative Name
- VTA1
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Background
- The VTA1 protein is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. This protein is involved in the sorting and down-regulation of EGFR (By similarity) and involved in HIV-1 budding.
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NCBI Accession
- NP_057569
Target
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