VTA1 antibody (AA 1-307)

Catalog No. ABIN5776242

This Mouse Monoclonal antibody specifically detects VTA1 in ELISA, WB, IF, ICC and FACS. It exhibits reactivity toward Human.

Quick Overview for VTA1 antibody (AA 1-307) (ABIN5776242)

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VTA1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: AT14G10

Product Details anti-VTA1 Antibody

Binding Specificity: AA 1-307

Purpose: Human VTA1 antibody

Purification: Purified

Immunogen: Recombinant human VTA1 (1-307aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for VTA1

Target: VTA1 (Vps20-Associated 1 Homolog (VTA1))

Alternative Name: VTA1

Background: The VTA1 protein is involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. This protein is involved in the sorting and down-regulation of EGFR (By similarity) and involved in HIV-1 budding.

NCBI Accession: NP_057569