Caspase 5 p10 antibody (Cleaved-Ser331)

Catalog No. ABIN5955945

The Rabbit Polyclonal anti-Caspase 5 p10 antibody has been validated for WB and ELISA. It is suitable to detect Caspase 5 p10 in samples from Human.

Quick Overview for Caspase 5 p10 antibody (Cleaved-Ser331) (ABIN5955945)

Target: Caspase 5 p10

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 5 p10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Caspase 5 p10 Antibody

Binding Specificity: Cleaved-Ser331

Specificity: Apoptosis related cysteine protease,CASP-5,CASP5,CASP5,Caspase-5 subunit p10,ICE(rel)-III,ICERELIII,ICH 3,ICH 3 protease,Protease ICH-3,Protease TY,TY,TY protease

Purification: Affinity purification

Immunogen: Synthesized peptide derived from the C-terminal region of human Caspase-5 p10

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:20000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Caspase 5 p10

Target: Caspase 5 p10

Alternative Name: Caspase-5 p10

Background: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene.

Molecular Weight: 48kDa

Gene ID: 838

UniProt: P51878