c-FOS antibody (Thr232)

Catalog No. ABIN5958112

This anti-c-FOS antibody is a Rabbit Polyclonal antibody detecting c-FOS in WB, ELISA and IHC (p). Suitable for Human, Rat and Mouse.

Quick Overview for c-FOS antibody (Thr232) (ABIN5958112)

Target: c-FOS (c-Fos) (c-Fos)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This c-FOS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-c-FOS Antibody

Binding Specificity: Thr232

Specificity: Activator protein 1,AP 1,C FOS,Cellular oncogene c fos,Cellular oncogene fos,FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS),FBJ murine osteosarcoma viral oncogene homolog,FBJ murine osteosarcoma viral v fos oncogene homolog,FBJ Osteosarcoma Virus,FOS,FOS protein,FOS,G0 G1 switch regulatory protein 7,G0/G1 switch regulatory protein 7,G0S7,Oncogene FOS,p55,proto oncogene c Fos,Proto oncogene protein c fos,Proto-oncogene c-Fos,v fos FBJ murine osteosarcoma viral oncogene homolog

Purification: Affinity purification

Immunogen: Synthesized peptide derived from human c-Fos around the non-phosphorylation site of Thr232.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for c-FOS

Target: c-FOS (c-Fos) (c-Fos)

Alternative Name: c-Fos

Background: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation.

Molecular Weight: 41kDa

Gene ID: 2353

UniProt: P01100

Pathways: S100 Proteins