Histone 3 antibody (pSer10)
Quick Overview for Histone 3 antibody (pSer10) (ABIN5962591)
Target
See all Histone 3 (H3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer10
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Specificity
- HIST1H3A,H3FA,HIST1H3B,H3FL,HIST1H3C,H3FC,HIST1H3D,H3FB,HIST1H3E,H3FD,HIST1H3F,H3FI,HIST1H3G,H3FH,HIST1H3H,H3FK,HIST1H3I,H3FF,HIST1H3J,H3FJ,Histone H3.1,Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3
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Purification
- Affinity purification
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Immunogen
- Synthesized peptide derived from human Histone H3 around the phosphorylation site of Ser10
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Histone 3 (H3) (Histone H3 (H3))
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Alternative Name
- Histone H3
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Background
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Molecular Weight
- 15kDa
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Gene ID
- 8350, 8351, 8352
Target
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