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CD40 antibody (Extracellular Domain)

This anti-CD40 antibody is a Rat Monoclonal antibody detecting CD40 in FACS, ELISA, IHC, Func and IHC (fro). Suitable for Mouse.
Catalog No. ABIN600789

Quick Overview for CD40 antibody (Extracellular Domain) (ABIN600789)

Target

See all CD40 Antibodies
CD40

Reactivity

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Mouse

Host

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Rat

Clonality

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Monoclonal

Conjugate

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This CD40 antibody is un-conjugated

Application

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Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Binding Specificity

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    Extracellular Domain

    Specificity

    Recognizes mouse CD40. It does not react with normal mouse Ig or with human IgG1 and will stain most mature mouse B cells. It does not cross-react with mouse T cells.

    Purification

    Protein G purified

    Immunogen

    Extracellular Domain of Mouse CD40 and the Fc portion of Human IgG1.

    Type of Immunogen: Fusion protein

    Isotype

    IgG2a
  • Application Notes

    Approved: ELISA, Flo (1:50), Func, IHC, IHC-Fr

    Usage: Suitable for use in ELISA, Flow Cytometry, Immunohistochemistry (frozen), and Functional Assays. Flow cytometry: 1:50, 10 μL labels 10^6 cells in 100 μL.

    Comment

    Target Species of Antibody: Mouse

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.4. No preservative added

    Preservative

    Without preservative

    Handling Advice

    Avoid repeated freezing and thawing

    Storage

    4 °C,-20 °C

    Storage Comment

    May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.
  • Target

    CD40

    Alternative Name

    CD40

    Background

    Name/Gene ID: CD40
    Family: TNF Receptor

    Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5

    Gene ID

    958

    UniProt

    P25942

    Pathways

    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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