CD166 antibody (Biotin)

Catalog No. ABIN610440

Cited in 4+ publications. The Biotin-conjugated Mouse Monoclonal anti-CD166 antibody (Clone 3A6) (ABIN610440) specifically detects CD166 in FACS and Func. The antibody is reactive with Human samples.

Quick Overview for CD166 antibody (Biotin) (ABIN610440)

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD166 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: 3A6

Product Details anti-CD166 Antibody (Biotin)

Specificity: CD166 Molecule of 100 kd.

Purification: Protein A purified

Immunogen: Human thymic epithelial cells.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func

Usage: Function: Blocks binding of CD6 to CD166. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-CD166 antibody (Biotin) (ABIN610440)

Faigle, Colucci-Guyon, Louvard, Amigorena, Galli: "Vimentin filaments in fibroblasts are a reservoir for SNAP23, a component of the membrane fusion machinery." in: Molecular biology of the cell, Vol. 11, Issue 10, pp. 3485-94, (2000) (PubMed).

Ramalho-Santos, Moreno, Sutovsky, Chan, Hewitson, Wessel, Simerly, Schatten: "SNAREs in mammalian sperm: possible implications for fertilization." in: Developmental biology, Vol. 223, Issue 1, pp. 54-69, (2000) (PubMed).

Kee, Lin, Hsu, Scheller: "Distinct domains of syntaxin are required for synaptic vesicle fusion complex formation and dissociation." in: Neuron, Vol. 14, Issue 5, pp. 991-8, (1995) (PubMed).

Bennett, Calakos, Scheller: "Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones." in: Science (New York, N.Y.), Vol. 257, Issue 5067, pp. 255-9, (1992) (PubMed).

Target Details for CD166

Target: CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))

Alternative Name: ALCAM / CD166

Background: Name/Gene ID: ALCAM

Synonyms: ALCAM, CD166 antigen, MEMD, CD166

Gene ID: 214

UniProt: Q13740