RNF166 antibody

Catalog No. ABIN6135037

This Rabbit Polyclonal antibody specifically detects RNF166 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for RNF166 antibody (ABIN6135037)

Target: RNF166 (Ring Finger Protein 166 (RNF166))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF166 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-RNF166 Antibody

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide of human RNF166

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IF,1:20 - 1:50

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RNF166

Target: RNF166 (Ring Finger Protein 166 (RNF166))

Alternative Name: RNF166

Background: E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Plays also a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication.,RNF166,Cell Biology & Developmental Biology,Ubiquitin,RNF166

Molecular Weight: 14 kDa/17 kDa/26 kDa

Gene ID: 115992

UniProt: Q96A37