ACD antibody (AA 1-220)

Catalog No. ABIN6136425

This Rabbit Polyclonal antibody specifically detects ACD in WB. It exhibits reactivity toward Human.

Quick Overview for ACD antibody (AA 1-220) (ABIN6136425)

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACD antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ACD Antibody

Binding Specificity: AA 1-220

Sequence: MPGRCQSDAA MRVNGPASRA PAGWTSGSLH TGPRAGRPRA QARGVRGRGL LLRPRPAKEL PLPRKGGAWA PAGNPGPLHP LGVAVGMAGS GRLVLRPWIR ELILGSETPS SPRAGQLLEV LQDAEAAVAG PSHAPDTSDV GATLLVSDGT HSVRCLVTRE ALDTSDWEEK EFGFRGTEGR LLLLQDCGVH VQVAEGGAPA EFYLQVDRFS LLPTEQPRLR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACD (NP_001075955.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ACD

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Alternative Name: ACD

Background: This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.,ACD,PIP1,PTOP,TINT1,TPP1,ACD

Molecular Weight: 57 kDa

Gene ID: 65057

UniProt: Q96AP0

Pathways: Telomere Maintenance