AIPL1 antibody (AA 1-384)

Catalog No. ABIN6136691

The Rabbit Polyclonal anti-AIPL1 antibody has been validated for WB, IHC and IF. It is suitable to detect AIPL1 in samples from Human.

Quick Overview for AIPL1 antibody (AA 1-384) (ABIN6136691)

Target: AIPL1 (Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AIPL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-AIPL1 Antibody

Binding Specificity: AA 1-384

Sequence: MDAALLLNVE GVKKTILHGG TGELPNFITG SRVIFHFRTM KCDEERTVID DSRQVGQPMH IIIGNMFKLE VWEILLTSMR VHEVAEFWCD TIHTGVYPIL SRSLRQMAQG KDPTEWHVHT CGLANMFAYH TLGYEDLDEL QKEPQPLVFV IELLQVDAPS DYQRETWNLS NHEKMKAVPV LHGEGNRLFK LGRYEEASSK YQEAIICLRN LQTKEKPWEV QWLKLEKMIN TLILNYCQCL LKKEEYYEVL EHTSDILRHH PGIVKAYYVR ARAHAEVWNE AEAKADLQKV LELEPSMQKA VRRELRLLEN RMAEKQEEER LRCRNMLSQG ATQPPAEPPT EPPAQSSTEP PAEPPTAPSA ELSAGPPAEP ATEPPPSPGH SLQH

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human AIPL1 (NP_055151.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AIPL1

Target: AIPL1 (Aryl Hydrocarbon Receptor Interacting Protein-Like 1 (AIPL1))

Alternative Name: AIPL1

Background: Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5 % of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20 % of recessive LCA. Alternative splicing results in multiple transcript variants.,AIPL1,AIPL2,LCA4,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,AIPL1

Molecular Weight: 36 kDa/40 kDa/41 kDa/43 kDa

Gene ID: 23746

UniProt: Q9NZN9