ALOXE3 antibody (AA 1-280)

Catalog No. ABIN6136820

This anti-ALOXE3 antibody is a Rabbit Polyclonal antibody detecting ALOXE3 in WB. Suitable for Human.

Quick Overview for ALOXE3 antibody (AA 1-280) (ABIN6136820)

Target: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALOXE3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ALOXE3 Antibody

Binding Specificity: AA 1-280

Sequence: MAVYRLCVTT GPYLRAGTLD NISVTLVGTC GESPKQRLDR MGRDFAPGSV QKYKVRCTAE LGELLLLRVH KERYAFFRKD SWYCSRICVT EPDGSVSHFP CYQWIEGYCT VELRPGTART ICQDSLPLLL DHRTRELRAR QECYRWKIYA PGFPCMVDVN SFQEMESDKK FALTKTTTCV DQGDSSGNRY LPGFPMKIDI PSLMYMEPNV RYSATKTISL LFNAIPASLG MKLRGLLDRK GSWKKLDDMQ NIFWCHKTFT TKYVTEHWCE DHFFGYQYLN

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ALOXE3 (NP_067641.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ALOXE3

Target: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Alternative Name: ALOXE3

Background: This gene is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE). Multiple transcript variants encoding different isoforms have been found for this gene.,ALOXE3,ARCI3,E-LOX,eLOX-3,eLOX3,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Endocrine & Metabolism,Lipid Metabolism,ALOXE3

Molecular Weight: 80 kDa/95 kDa

Gene ID: 59344

UniProt: Q9BYJ1

Pathways: Cell-Cell Junction Organization