APOC1 antibody (AA 1-83)

Catalog No. ABIN6137012

The Rabbit Polyclonal anti-APOC1 antibody has been validated for IHC. It is suitable to detect APOC1 in samples from Human.

Quick Overview for APOC1 antibody (AA 1-83) (ABIN6137012)

Target: APOC1 (Apolipoprotein C-I (APOC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-APOC1 Antibody

Binding Specificity: AA 1-83

Sequence: MRLFLSLPVL VVVLSIVLEG PAPAQGTPDV SSALDKLKEF GNTLEDKARE LISRIKQSEL SAKMREWFSE TFQKVKEKLK IDS

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-83 of human APOC1 (NP_001636.1).

Isotype: IgG

Application Details

Application Notes: IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for APOC1

Target: APOC1 (Apolipoprotein C-I (APOC1))

Alternative Name: APOC1

Background: This gene encodes a member of the apolipoprotein C1 family. This gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. The encoded protein plays a central role in high density lipoprotein (HDL) and very low density lipoprotein (VLDL) metabolism. This protein has also been shown to inhibit cholesteryl ester transfer protein in plasma. A pseudogene of this gene is located 4 kb downstream in the same orientation, on the same chromosome. This gene is mapped to chromosome 19, where it resides within a apolipoprotein gene cluster. Alternative splicing and the use of alternative promoters results in multiple transcript variants.,APOC1,Apo-CI,ApoC-I,apo-CIB,apoC-IB,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Heart,Lipids,Fatty Acids,Lipoproteins/Apolipoproteins,Cardiovascular diseases,Heart disease,APOC1

Molecular Weight: 9 kDa

Gene ID: 341

UniProt: P02654

Pathways: Apoptosis