AQR antibody (AA 400-700)

Catalog No. ABIN6137057

This Rabbit Polyclonal antibody specifically detects AQR in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for AQR antibody (AA 400-700) (ABIN6137057)

Target: AQR (Aquarius Homolog (AQR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AQR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-AQR Antibody

Binding Specificity: AA 400-700

Sequence: KEFLLELLVS RHERRISQIQ QLNQMPLYPT EKIIWDENIV PTEYYSGEGC LALPKLNLQF LTLHDYLLRN FNLFRLESTY EIRQDIEDSV SRMKPWQSEY GGVVFGGWAR MAQPIVAFTV VEVAKPNIGE NWPTRVRADV TINLNVRDHI KDEWEGLRKH DVCFLITVRP TKPYGTKFDR RRPFIEQVGL VYVRGCEIQG MLDDKGRVIE DGPEPRPNLR GESRTFRVFL DPNQYQQDMT NTIQNGAEDV YETFNIIMRR KPKENNFKAV LETIRNLMNT DCVVPDWLHD IILGYGDPSS A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human AQR (NP_055506.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for AQR

Target: AQR (Aquarius Homolog (AQR))

Alternative Name: AQR

Background: Involved in pre-mRNA splicing as component of the spliceosome. Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint during the late stages of splicing. Has ATP-dependent RNA helicase activity and can unwind double-stranded RNA molecules with a 3' overhang (in vitro.,AQR,IBP160,fSAP164,Epigenetics & Nuclear Signaling,RNA Binding,AQR

Molecular Weight: 171 kDa

Gene ID: 9716

UniProt: O60306