Arhgef9 antibody (AA 307-516)
Quick Overview for Arhgef9 antibody (AA 307-516) (ABIN6137098)
Target
See all Arhgef9 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 307-516
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Sequence
- WEGEDILDRS SELIYTGEMA WIYQPYGRNQ QRVFFLFDHQ MVLCKKDLIR RDILYYKGRI DMDKYEVVDI EDGRDDDFNV SMKNAFKLHN KETEEIHLFF AKKLEEKIRW LRAFREERKM VQEDEKIGFE ISENQKRQAA MTVRKVPKQK GVNSARSVPP SYPPPQDPLN HGQYLVPDGI AQSQVFEFTE PKRSQSPFWQ NFSRLTPFKK
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 307-516 of human ARHGEF9 (NP_056000.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Comment
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HIGH QUALITY
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Arhgef9 (Cdc42 Guanine Nucleotide Exchange Factor (GEF) 9 (Arhgef9))
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Alternative Name
- ARHGEF9
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Background
- The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.,ARHGEF9,COLLYBISTIN,EIEE8,HPEM-2,PEM-2,PEM2,Signal Transduction,G protein signaling,Signal Transduction,ARHGEF9
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Molecular Weight
- 49 kDa/54 kDa/60 kDa
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Gene ID
- 23229
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UniProt
- O43307
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Pathways
- Neurotrophin Signaling Pathway
Target
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