ATOX1 antibody (AA 1-68)

Catalog No. ABIN6137289

The Rabbit Polyclonal anti-ATOX1 antibody has been validated for WB. It is suitable to detect ATOX1 in samples from Human.

Quick Overview for ATOX1 antibody (AA 1-68) (ABIN6137289)

Target: ATOX1 (ATX1 Antioxidant Protein 1 Homolog (ATOX1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATOX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATOX1 Antibody

Binding Specificity: AA 1-68

Sequence: MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LLATLKKTGK TVSYLGLE

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human ATOX1 (NP_004036.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATOX1

Target: ATOX1 (ATX1 Antioxidant Protein 1 Homolog (ATOX1))

Alternative Name: ATOX1

Background: This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.,ATOX1,ATX1,HAH1,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,ATOX1

Molecular Weight: 7 kDa

Gene ID: 475

UniProt: O00244

Pathways: Transition Metal Ion Homeostasis