Azurocidin antibody (AA 27-251)

Catalog No. ABIN6137391

The Rabbit Polyclonal anti-Azurocidin antibody has been validated for WB. It is suitable to detect Azurocidin in samples from Human.

Quick Overview for Azurocidin antibody (AA 27-251) (ABIN6137391)

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Azurocidin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Azurocidin Antibody

Binding Specificity: AA 27-251

Sequence: IVGGRKARPR QFPFLASIQN QGRHFCGGAL IHARFVMTAA SCFQSQNPGV STVVLGAYDL RRRERQSRQT FSISSMSENG YDPQQNLNDL MLLQLDREAN LTSSVTILPL PLQNATVEAG TRCQVAGWGS QRSGGRLSRF PRFVNVTVTP EDQCRPNNVC TGVLTRRGGI CNGDGGTPLV CEGLAHGVAS FSLGPCGRGP DFFTRVALFR DWIDGVLNNP GPGPA

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 27-251 of human AZU1 (NP_001691.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Azurocidin

Target: Azurocidin (AZU1) (Azurocidin 1 (AZU1))

Alternative Name: AZU1

Background: Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. This gene encodes a preproprotein that is proteolytically processed to generate a mature azurophil granule antibiotic protein, with monocyte chemotactic and antimicrobial activity. It is also an important multifunctional inflammatory mediator. This encoded protein is a member of the serine protease gene family but it is not a serine proteinase, because the active site serine and histidine residues are replaced. The genes encoding this protein, neutrophil elastase 2, and proteinase 3 are in a cluster located at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation.,AZU1,AZAMP,AZU,CAP37,HBP,HUMAZUR,NAZC,hHBP,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,Cardiovascular,AZU1

Molecular Weight: 26 kDa

Gene ID: 566

UniProt: P20160