BAIAP2 antibody (AA 362-521)

Catalog No. ABIN6137432

The Rabbit Polyclonal anti-BAIAP2 antibody has been validated for WB and IF. It is suitable to detect BAIAP2 in samples from Human.

Quick Overview for BAIAP2 antibody (AA 362-521) (ABIN6137432)

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAIAP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-BAIAP2 Antibody

Binding Specificity: AA 362-521

Sequence: PRSSSMAAGL ERNGRMRVKA IFSHAAGDNS TLLSFKEGDL ITLLVPEARD GWHYGESEKT KMRGWFPFSY TRVLDSDGSD RLHMSLQQGK SSSTGNLLDK DDLAIPPPDY GAASRAFPAQ TASGFKQRPY SVAVPAFSQG LDDYGARSMS SGSGTLVSTV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 362-521 of human BAIAP2 (NP_059344.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BAIAP2

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Alternative Name: BAIAP2

Background: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,BAIAP2,BAP2,FLAF3,IRSP53,Neuroscience,Cell Type Marker,Neuron marker,Growth Cone,BAIAP2

Molecular Weight: 56 kDa/57 kDa/59 kDa/60 kDa

Gene ID: 10458

UniProt: Q9UQB8