BCAS3 antibody (AA 674-913)

Catalog No. ABIN6137481

This anti-BCAS3 antibody is a Rabbit Polyclonal antibody detecting BCAS3 in IHC, WB, IP and IF. Suitable for Human.

Quick Overview for BCAS3 antibody (AA 674-913) (ABIN6137481)

Target: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAS3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-BCAS3 Antibody

Binding Specificity: AA 674-913

Sequence: LAGLVPPGSP GPITRHGSYD SLASDHSGQE DEEWLSQVEI VTHTGPHRRL WMGPQFQFKT IHPSGQTTVI SSSSSVLQSH GPSDTPQPLL DFDTDDLDLN SLRIQPVRSD PVSMPGSSRP VSDRRGVSTV IDAASGTFDR SVTLLEVCGS WPEGFGLRHM SSMEHTEEGL RERLADAMAE SPSRDVVGSG TELQREGSIE TLSNSSGSTS GSIPRNFDGY RSPLPTNESQ PLSLFPTGFP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 674-913 of human BCAS3 (NP_060149.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BCAS3

Target: BCAS3 (Breast Carcinoma Amplified Sequence 3 (BCAS3))

Alternative Name: BCAS3

Background: Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation (By similarity. Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin. Plays a regulatory role in autophagic activity. In complex with PHAF1, associates with the preautophagosomal structure during both non-selective and selective autophagy. Probably binds phosphatidylinositol 3-phosphate (PtdIns3P which would mediate the recruitment preautophagosomal structures.,BCAS3,GAOB1,MAAB,Cancer,Tumor biomarkers,Stem Cells,Cancer Stem Cells,BCAS3

Molecular Weight: 74 kDa/99 kDa/101 kDa/102 kDa/103 kDa

Gene ID: 54828

UniProt: Q9H6U6