C7orf27
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB,1:500 - 1:2000,IHC,1:50 - 1:100
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
BAAT1 (C7orf27)
(Chromosome 7 Open Reading Frame 27 (C7orf27))
Alternative Name
BRAT1
Background
The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM.,BRAT1,BAAT1,C7orf27,RMFSL,Epigenetics & Nuclear Signaling,DNA Damage & Repair,BRAT1