BTN3A1 antibody (AA 40-250)

Catalog No. ABIN6137698

This Rabbit Polyclonal antibody specifically detects BTN3A1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for BTN3A1 antibody (AA 40-250) (ABIN6137698)

Target: BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BTN3A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BTN3A1 Antibody

Binding Specificity: AA 40-250

Sequence: ILAMVGEDAD LPCHLFPTMS AETMELKWVS SSLRQVVNVY ADGKEVEDRQ SAPYRGRTSI LRDGITAGKA ALRIHNVTAS DSGKYLCYFQ DGDFYEKALV ELKVAALGSD LHVDVKGYKD GGIHLECRST GWYPQPQIQW SNNKGENIPT VEAPVVADGV GLYAVAASVI MRGSSGEGVS CTIRSSLLGL EKTASISIAD PFFRSAQRWI A

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human BTN3A1 (NP_008979.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BTN3A1

Target: BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))

Alternative Name: BTN3A1

Background: The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1, MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010],BTN3A1,BT3.1,BTF5,BTN3.1,CD277,Immunology & Inflammation,CD markers,BTN3A1

Molecular Weight: 39 kDa/41 kDa/52 kDa/57 kDa

Gene ID: 11119

UniProt: O00481

Pathways: Activated T Cell Proliferation