CCDC61 antibody (AA 352-531)

Catalog No. ABIN6138042

This Rabbit Polyclonal antibody specifically detects CCDC61 in WB. It exhibits reactivity toward Human.

Quick Overview for CCDC61 antibody (AA 352-531) (ABIN6138042)

Target: CCDC61 (Coiled-Coil Domain Containing 61 (CCDC61))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC61 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCDC61 Antibody

Binding Specificity: AA 352-531

Sequence: PSPSPTGGRA LRFDPTAFVK AKERKQREIQ MKQQQRNRLG SGGSGDGPSV SWSRQTQPPA ALTGRGDAPN RSRNRSSSVD SFRSRCSSAS SCSDLEDFSE SLSRGGHRRR GKPPSPTPWS GSNMKSPPVE RSHHQKSLAN SGGWVPIKEY SSEHQAADMA EIDARLKALQ EYMNRLDMRS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 352-531 of human CCDC61 (NP_001073871.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CCDC61

Target: CCDC61 (Coiled-Coil Domain Containing 61 (CCDC61))

Alternative Name: CCDC61

Background: Microtubule-binding centrosomal protein required for centriole cohesion, independently of the centrosome-associated protein/CEP250 and rootletin/CROCC linker. In interphase, required for anchoring microtubule at the mother centriole subdistal appendages and for centrosome positioning. During mitosis, may be involved in spindle assembly and chromatin alignment by regulating the organization of spindle microtubules into a symmetrical structure. Has been proposed to play a role in CEP170 recruitment to centrosomes. However, this function could not be confirmed. Plays a non-essential role in ciliogenesis.,CCDC61,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,CCDC61

Molecular Weight: 37 kDa/57 kDa

Gene ID: 729440

UniProt: Q9Y6R9