CD163 antibody (AA 750-1050)

Catalog No. ABIN6138118

This Rabbit Polyclonal antibody specifically detects CD163 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for CD163 antibody (AA 750-1050) (ABIN6138118)

Target: CD163

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD163 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-CD163 Antibody

Binding Specificity: AA 750-1050

Sequence: LSDAHVVCRQ LGCGEAINAT GSAHFGEGTG PIWLDEMKCN GKESRIWQCH SHGWGQQNCR HKEDAGVICS EFMSLRLTSE ASREACAGRL EVFYNGAWGT VGKSSMSETT VGVVCRQLGC ADKGKINPAS LDKAMSIPMW VDNVQCPKGP DTLWQCPSSP WEKRLASPSE ETWITCDNKI RLQEGPTSCS GRVEIWHGGS WGTVCDDSWD LDDAQVVCQQ LGCGPALKAF KEAEFGQGTG PIWLNEVKCK GNESSLWDCP ARRWGHSECG HKEDAAVNCT DISVQKTPQK ATTGRSSRQS S

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 750-1050 of human CD163 (NP_004235.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD163

Target: CD163

Alternative Name: CD163

Background: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,CD163,M130,MM130,SCARI1,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,CD163

Molecular Weight: 121 kDa/124 kDa/125 kDa

Gene ID: 9332

UniProt: Q86VB7