Chromogranin A antibody (AA 230-380)

Catalog No. ABIN6138527

This Rabbit Polyclonal antibody specifically detects Chromogranin A in WB. It exhibits reactivity toward Human.

Quick Overview for Chromogranin A antibody (AA 230-380) (ABIN6138527)

Target: Chromogranin A (CHGA)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Chromogranin A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Chromogranin A Antibody

Binding Specificity: AA 230-380

Sequence: EEEEEEEAEA GEEAVPEEEG PTVVLNPHPS LGYKEIRKGE SRSEALAVDG AGKPGAEEAQ DPEGKGEQEH SQQKEEEEEM AVVPQGLFRG GKSGELEQEE ERLSKEWEDS KRWSKMDQLA KELTAEKRLE GQEEEEDNRD SSMKLSFRAR A

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 230-380 of human CHGA (NP_001266.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Chromogranin A

Target: Chromogranin A (CHGA)

Alternative Name: CHGA

Background: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides, vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene.,CHGA,CGA,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Insulin and insulin-like,Neuroscience,Cell Type Marker,Neuron marker,CHGA

Molecular Weight: 50 kDa

Gene ID: 1113

UniProt: P10645

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling