CHRNB1 antibody (AA 25-235)

Catalog No. ABIN6138587

This Rabbit Polyclonal antibody specifically detects CHRNB1 in WB. It exhibits reactivity toward Human.

Quick Overview for CHRNB1 antibody (AA 25-235) (ABIN6138587)

Target: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHRNB1 Antibody

Binding Specificity: AA 25-235

Sequence: EAEGRLREKL FSGYDSSVRP AREVGDRVRV SVGLILAQLI SLNEKDEEMS TKVYLDLEWT DYRLSWDPAE HDGIDSLRIT AESVWLPDVV LLNNNDGNFD VALDISVVVS SDGSVRWQPP GIYRSSCSIQ VTYFPFDWQN CTMVFSSYSY DSSEVSLQTG LGPDGQGHQE IHIHEGTFIE NGQWEIIHKP SRLIQPPGDP RGGREGQRQE V

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-235 of human CHRNB1 (NP_000738.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHRNB1

Target: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Alternative Name: CHRNB1

Background: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.,CHRNB1,ACHRB,CHRNB,CMS1D,CMS2A,CMS2C,SCCMS,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRNB1

Molecular Weight: 49 kDa/56 kDa

Gene ID: 1140

UniProt: P11230

Pathways: Synaptic Membrane