Claudin 2 antibody (AA 30-230)

Catalog No. ABIN6138683

The Rabbit Polyclonal anti-Claudin 2 antibody has been validated for WB. It is suitable to detect Claudin 2 in samples from Human.

Quick Overview for Claudin 2 antibody (AA 30-230) (ABIN6138683)

Target: Claudin 2 (CLDN2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Claudin 2 Antibody

Binding Specificity: AA 30-230

Sequence: WKTSSYVGAS IVTAVGFSKG LWMECATHST GITQCDIYST LLGLPADIQA AQAMMVTSSA ISSLACIISV VGMRCTVFCQ ESRAKDRVAV AGGVFFILGG LLGFIPVAWN LHGILRDFYS PLVPDSMKFE IGEALYLGII SSLFSLIAGI ILCFSCSSQR NRSNYYDAYQ AQPLATRSSP RPGQPPKVKS EFNSYSLTGY V

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-230 of human CLDN2 (NP_001164566.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Claudin 2

Target: Claudin 2 (CLDN2)

Alternative Name: CLDN2

Background: This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.,CLDN2,claudin-2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,CLDN2

Molecular Weight: 24 kDa

Gene ID: 9075

UniProt: P57739

Pathways: Hepatitis C